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You searched for: subject:"optogenetics"
[texts]Light Scattering Properties Vary Across Different Regions of the Adult Mouse Brain - Al-Juboori, Saif
Recently developed optogenetic tools provide powerful approaches to optically excite or inhibit neural activity. In a typical in-vivo experiment, light is delivered to deep nuclei via an implanted optical fiber. Light intensity attenuates with increasing distance from the fiber tip, determining the volume of tissue in which optogenetic proteins can successfully be activated. However, whether and how this volume of effective light intensity varies as a function of brain region or wavelength has n...
Keywords: brain atlas; in-vivo; optical fiber; optogenetics; biomedical
Downloads: 93
[texts]Optogenetic control of genetically-targeted pyramidal neuron activity in prefrontal cortex - Donald C. Cooper Ph.D.
A salient feature of prefrontal cortex organization is the vast diversity of cell types that support the temporal integration of events required for sculpting future responses. A major obstacle in understanding the routing of information among prefrontal neuronal subtypes is the inability to manipulate the electrical activity of genetically defined cell types over behaviorally relevant timescales and activity patterns...
Keywords: optogenetics; prefrontal cortex; optrodes; electrophysiology;
Downloads: 74
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